Needle-less Serum - DRMTLGY
Needle-less Serum
Needle-less Serum
Needle-less Serum
Needle-less Serum - DRMTLGY
Needle-less Serum

Needle-less Serum

1 fl oz

Free U.S. Shipping Over $40, and a risk-free guarantee!

If you don't love it, return it within 60 days for a full-refund - just contact us and we'll take care of you

Needle-less Serum is a twice-a-day serum that safely targets the appearance of fine lines around the mouth, eyes, and forehead, while also hydrating the skin to give a radiant glow! Our advanced formula helps with signs of aging by strengthening the skin’s moisture barrier, while improving the look of skin fullness and pore appearance. Now formulated with our proprietary Cerapep® Technology: a revolutionary blend of restorative peptides & ceramides.

  • Our best-selling product
  • Works with any other skin care product and regimen
  • Absorbs quickly and doesn't leave a greasy residue



This product is suggested for people looking to:

  • Target the appearance of fine lines around the mouth, forehead, and eyes
  • Promotes a youthful appearance
  • Improve appearance in skin’s smoothness

Why Needle-less Serum?

Treat yourself to our most popular anti-aging serum. We know that this isn’t a facelift in a bottle. However, we have combined a potent blend of multiple revolutionary active ingredients to give your skin what it needs.

It's gentle on the skin, non-greasy, non-comedogenic and is suitable for any skin care routine!

Peer Reviewed Articles

Cosmeceuticals and Cosmetic Practice, November 2013, Chapter 10
Journal of Cosmetic Dermatology, April 2004, Volume 3, Issue 2, pages 88-93
British Journal of Dermatology, September 2000, Volume 143, Issue 3, pages 524-531
Journal of Drugs in Dermatology, December 2015, Volume 15, 1 Supplement 2, pages s24-37
Journal of Drugs in Dermatology, September 2011, Volume 10, Issue 9, pages 990-1000
Journal of Cosmetic Dermatology, February 2019, Volume 18, Issue 1, pages 346-354
Journal of Cosmetic Dermatology, June 2007, Volume 6, Issue 2, pages 75-82

Suitable For These Skin Types

animal derm fragrance_free gluten_free paraben_free sulfate_free

Ingredients designed for your skin.

Niacinamide (Vitamin B3)

A multifaceted ingredient with numerous skin care benefits.

Hyaluronic Acid

A naturally occurring carbohydrate in the human body that is responsible for keeping skin plump and hydrated.

Copper Peptides

Helps with multiple signs of aging.


Fundamental components of skin tissue, essentially a group of complex proteins.

Pea Extract

Provides antioxidant and anti-inflammatory benefits.

Glucosamine HCI

These compounds have been reported to have several beneficial effects on the skin or skin cells.

Sodium Chondroitin Sulfate

Used as a skin-conditioning agent.

Bambusa Vulgaris Leaf/Stem Extract

The richest source of natural Silica.


Also known as Vitamin B5, is effective as a skin lubricant, emollient, and moisturizer.

Ceramides AP, NP, EOP

Naturally occurring long chains of fatty acids (lipids) that improve the look and feel of dry skin.

Palmitoyl Tripeptide-1

Synthetic fatty acid-linked peptide.

Palmitoyl Tripeptide-5

Synthetic peptide that plays a role in the appearance of skin firmness.

Palmitoyl Tripeptide-7

Synthetic peptide comprised of four amino acids and fatty acids.


A moisturizing phospholipid. 


  • Apply 4 to 5 drops onto fingers and smooth over a slightly damp face. Avoid getting too close to the eyes.
  • Allow to absorb before applying additional products.
  • Can be used twice a day or as directed by a physician.


Ingredient Highlights

Niacinamide (Vitamin B3), Hyaluronic Acid (Sodium Hyaluronate), Methyl Glucoside Phosphate Proline Lysine Copper Complex, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Sodium Chondroitin Sulfate, Glycosaminoglycans, Pea Extract, Glucosamine HCI, Panthenol (Provitamin B5), Bambusa Vulgaris Leaf/Stem Extract


All Ingredients

Water, Glycerin, Sodium Chondroitin Sulfate, Sodium Hyaluronate, Pisum Sativum (Pea) Extract, Bambusa Vulgaris Leaf/Stem Extract, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Glucosamine HCl, Glycosaminoglycans, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Phytosphingosine, Cholesterol, Niacinamide, Sodium Lauroyl Lactylate, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Panthenol, Tocopheryl Acetate, Phenoxyethanol, Polysorbate 20, Ethylhexylglycerin, Disodium EDTA, Butylene Glycol, Carbomer, Xanthan Gum

Skin Types

This product is suitable for these skin types.

Normal skin: No or few imperfections, no severe sensitivity, barely visible pores, a radiant complexion

Sensitive skin: Reaction to common ingredients, redness, itching, dryness

Dry skin: Dull complexion, rough complexion, red patches, more prone to wrinkles, skin is itchy and flaky

Oily skin: Skin appears shiny, enlarged pores, more prone to acne

Combination skin: Oily skin in some areas and dry skin in others.

Frequently Bought With

Customer Reviews

Based on 1505 reviews
Kim Howell

I used this serum everyday and have noticed a dramatic change in appearance! I cannot imagine not using this!

Ann Stephenson

I have been using this product 2 times a day for about 3 weeks and feel I am seeing a difference. My skin looks brighter and feels softer. Highly recommend.

Ashley Fooshee
Has fixed my skin

I started using this serum a few months ago and finally am starting to feel comfortable with my skin. It has made my skin smoother, more hydrated, and has really helped prevent breakouts. I will keep buying this as long as I can!

Absolutely Amazed!

Get it! At 60, I’ve tried quite a few serums. Every single one disappointed. I was blessed with good skin but some terrible life events aged me quickly. Then, I saw a video recommending Needle-less serum. After about 4 weeks, I definitely see a great change! My skin is supple, smooth, and younger looking again! Forehead lines are almost gone, frown lines greatly reduced, skin is supple again! My husband even complemented my ageless skin - a first!

Carol Garner
Great Serum

Love this Serum. I apply with my face a bit moist from the toner after washing my face with the cleanser, and it goes on smoothly. I guess that since I am using all the products they work well together and I can see the difference in my skin after using for 3 months.