Needle-less Serum

Firming Plumping Serum

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$69.00
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1 fl oz

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1 fl oz
2 fl oz

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Experience visibly lifted, firmer, and deeply hydrated skin—no injections needed. This multitasking powerhouse serum blends our proprietary Cerapep™ Technology with targeted peptides, ceramides, and sodium hyaluronate to visibly smooth wrinkles, calm sensitivity, and reinforce your skin’s natural barrier. The perfect swap to simplify your complicated routine for one serum that delivers visible youthful results.
  • Visibly smooths fine lines and wrinkles
  • Firms and lifts the appearance of sagging skin
  • Energizes dull texture and enhances elasticity
  • Reduces redness, evens tone, and soothes sensitivity
Experience visibly lifted, firmer, and deeply hydrated skin—no injections needed. This multitasking powerhouse serum ...

4 Reasons Everyone Loves Needle-less Serum

1. Cosmo’s “Best Peptide Serum”

This serum works. But don't take our word for it—Cosmopolitan named it the "Best Peptide Serum" in 2023.

2. Dramatic Anti-aging Results You Can See

This active-packed serum is loaded with anti-aging superstars like Hyaluronic Acid, Niacinamide, and our proprietary Cerapep® Technology: a revolutionary blend of restorative peptides & ceramides.

3. Visibly Diminishes Fine Lines

Enriched with potent actives clinically proven to visibly improve the look of fine lines and wrinkles around the mouth, eyes, and forehead.

4. Brighten the Look of Pigmentation

Niacinamide strengthens the skin’s moisture barrier, while improving the look of pigmentation and pore appearance.

Proven Results

Drmtlgy image
Drmtlgy image
Drmtlgy image
Needle-less Serum Before Needle-less Serum After

Before and After 60 Days Of Use

When used as directed. Unedited and not retouched. Results may vary.

As we age, our skin’s extracellular matrix begins to weaken—leading to loss of firmness, deeper creases, and uneven texture. Daily environmental stressors and harsh products can also compromise the skin barrier, leaving it more prone to sensitivity, redness, and dryness. Needle-less Serum was engineered to tackle all of these concerns in one powerhouse solution.

 

Our signature Cerapep™ Technology blends three skin-identical ceramides with a targeted peptide complex to replenish essential lipids and signal your skin to rebuild its structural integrity. This dual approach not only visibly lifts and firms, but also fortifies the barrier against future moisture loss and irritation. To further calm and balance, we’ve added niacinamide, a gentle vitamin B3 derivative known for reducing redness, refining pores, and regulating oil levels.

 

Hydration is key to younger-looking skin. Sodium hyaluronate, the salt form of hyaluronic acid with a smaller molecular weight, acts like a moisture magnet—holding up to 1,000× its weight in water—to plump out fine lines and refine texture. Meanwhile, pea extract and copper peptides support your skin’s own repair processes for improved elasticity and an even tone.

 

Whether you want to prolong your injectable results or prefer a non-invasive alternative, Needle-less Serum integrates seamlessly into any routine.

Directions

  • Apply 4 to 5 drops onto fingers and smooth over a slightly damp face. Avoid getting too close to the eyes.
  • Allow to absorb before applying additional products.
  • Can be used twice a day or as directed by a physician.

Ingredients

Ingredient Highlights

Niacinamide (Vitamin B3), Hyaluronic Acid (Sodium Hyaluronate), Methyl Glucoside Phosphate Proline Lysine Copper Complex, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Sodium Chondroitin Sulfate, Glycosaminoglycans, Pea Extract, Glucosamine HCI, Panthenol (Provitamin B5), Bambusa Vulgaris Leaf/Stem Extract

 

All Ingredients

Water, Glycerin, Sodium Chondroitin Sulfate, Sodium Hyaluronate, Pisum Sativum (Pea) Extract, Bambusa Vulgaris Leaf/Stem Extract, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Glucosamine HCl, Glycosaminoglycans, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Phytosphingosine, Cholesterol, Niacinamide, Sodium Lauroyl Lactylate, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Panthenol, Tocopheryl Acetate, Phenoxyethanol, Polysorbate 20, Ethylhexylglycerin, Disodium EDTA, Butylene Glycol, Carbomer, Xanthan Gum

Frequently Asked Questions

Yes, this serum is suitable for all skin types, including sensitive and oily skin. It's a perfect serum for those wanting anti-aging results without a heavy feel or irritation.

Yes, this serum pairs perfectly with retinoids in your evening routine. Apply serum first, allow to absorb fully before applying retinoid.

Consistency and patience is key. You will start to notice results in a few weeks but we recommend using 2X a day for 6-8 weeks to see real results.

Apply to slightly damp skin as the first step in your AM & PM routine after cleansing and toning.

Absolutely! This serum will prolong results of your injectables. If you do not get injectables, this makes for a perfect non-invasive alternative option.

Skin Concerns

  • Redness
  • Firmness
  • Wrinkles
  • Dryness
  • Post Procedure

Skin Types

  • Normal
  • Dry
  • Combination
  • Oily

How to Layer Your DRMTLGY Products

The Perfect Additions to Any Routine

Customer Reviews

Based on 4034 reviews
92%
(3710)
6%
(231)
1%
(44)
1%
(25)
1%
(24)
S
Sheri Cuthbert
Age: 55+
Skin type: Combination
I’m never without it!

Best wrinkle fighter there is! Bigger size saves me money!

J
Janet
Age: 55+
Skin type: Sensitive
Surprised!

I purchased this serum on whim because I had some reward points to use up. I was completely happy with my skin care routine and wasn’t looking for a new serum but, from day one, I saw visible firming, even tone and brightness. I use it twice a day on clean skin. It absorbs quickly, layers nicely with other products and my skin feels really soft. I will definitely buy it again.

K
Katie Cole
Age: 40 - 55
Skin type: Combination
Liquid Gold

I can't get enough of this Needless Serum! When there is a sale, which lets be honest is all the time, I always have a back up. I have noticed my fine lines around my mouth have almost disappeared. I'm a former smoker of almost 10 years and they were very pronounced. I'm so happy I've found DRMTLGY products.

D
Dawn Tielbar
Age: 55+
Skin type: Combination
Highly Impressed

I have to admit that I wasn’t expecting much from this product. I know it was hyped up to be excellent but I still had my doubts. However, after trying it for just a few days myself I found it to be a great choice. Truly moisturized my skin and I realized I could use much less of my actual moisturizer. My skin seems to glow! And a little really does go a long way. You’ve made a believer out of me!

J
Jennie S.
Absolutely brilliant

I’ve had Botox a few times however got the dreaded ‘droopy eyes’ 😳 and I decided to try this instead.
I’m incredibly impressed with this product. I’ve only been using this product for a few weeks and I can already see the difference.
Highly recommended

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