Needle-less Serum

Firming Plumping Serum

Reviews
$69.00
Best Seller
Read Reviews
1 fl oz

✷ Earn 69 points with DRMTLGY Rewards. Join →

1 fl oz
2 fl oz

Free U.S. Shipping Over $40, and a risk-free guarantee!

If you don't love it, return it within 60 days for a full-refund - just contact us and we'll take care of you

Experience visibly lifted, firmer, and deeply hydrated skin—no injections needed. This multitasking powerhouse serum blends our proprietary Cerapep™ Technology with targeted peptides, ceramides, and sodium hyaluronate to visibly smooth wrinkles, calm sensitivity, and reinforce your skin’s natural barrier. The perfect swap to simplify your complicated routine for one serum that delivers visible youthful results.
  • Visibly smooths fine lines and wrinkles
  • Firms and lifts the appearance of sagging skin
  • Energizes dull texture and enhances elasticity
  • Reduces redness, evens tone, and soothes sensitivity
Experience visibly lifted, firmer, and deeply hydrated skin—no injections needed. This multitasking powerhouse serum ...

4 Reasons Everyone Loves Needle-less Serum

1. Cosmo’s “Best Peptide Serum”

This serum works. But don't take our word for it—Cosmopolitan named it the "Best Peptide Serum" in 2023.

2. Dramatic Anti-aging Results You Can See

This active-packed serum is loaded with anti-aging superstars like Hyaluronic Acid, Niacinamide, and our proprietary Cerapep® Technology: a revolutionary blend of restorative peptides & ceramides.

3. Visibly Diminishes Fine Lines

Enriched with potent actives clinically proven to visibly improve the look of fine lines and wrinkles around the mouth, eyes, and forehead.

4. Brighten the Look of Pigmentation

Niacinamide strengthens the skin’s moisture barrier, while improving the look of pigmentation and pore appearance.

Proven Results

Drmtlgy image
Drmtlgy image
Drmtlgy image
Needle-less Serum Before Needle-less Serum After

Before and After 60 Days Of Use

When used as directed. Unedited and not retouched. Results may vary.

As we age, our skin’s extracellular matrix begins to weaken—leading to loss of firmness, deeper creases, and uneven texture. Daily environmental stressors and harsh products can also compromise the skin barrier, leaving it more prone to sensitivity, redness, and dryness. Needle-less Serum was engineered to tackle all of these concerns in one powerhouse solution.

 

Our signature Cerapep™ Technology blends three skin-identical ceramides with a targeted peptide complex to replenish essential lipids and signal your skin to rebuild its structural integrity. This dual approach not only visibly lifts and firms, but also fortifies the barrier against future moisture loss and irritation. To further calm and balance, we’ve added niacinamide, a gentle vitamin B3 derivative known for reducing redness, refining pores, and regulating oil levels.

 

Hydration is key to younger-looking skin. Sodium hyaluronate, the salt form of hyaluronic acid with a smaller molecular weight, acts like a moisture magnet—holding up to 1,000× its weight in water—to plump out fine lines and refine texture. Meanwhile, pea extract and copper peptides support your skin’s own repair processes for improved elasticity and an even tone.

 

Whether you want to prolong your injectable results or prefer a non-invasive alternative, Needle-less Serum integrates seamlessly into any routine.

Directions

  • Apply 4 to 5 drops onto fingers and smooth over a slightly damp face. Avoid getting too close to the eyes.
  • Allow to absorb before applying additional products.
  • Can be used twice a day or as directed by a physician.

Ingredients

Ingredient Highlights

Niacinamide (Vitamin B3), Hyaluronic Acid (Sodium Hyaluronate), Methyl Glucoside Phosphate Proline Lysine Copper Complex, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Sodium Chondroitin Sulfate, Glycosaminoglycans, Pea Extract, Glucosamine HCI, Panthenol (Provitamin B5), Bambusa Vulgaris Leaf/Stem Extract

 

All Ingredients

Water, Glycerin, Sodium Chondroitin Sulfate, Sodium Hyaluronate, Pisum Sativum (Pea) Extract, Bambusa Vulgaris Leaf/Stem Extract, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Glucosamine HCl, Glycosaminoglycans, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Phytosphingosine, Cholesterol, Niacinamide, Sodium Lauroyl Lactylate, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Panthenol, Tocopheryl Acetate, Phenoxyethanol, Polysorbate 20, Ethylhexylglycerin, Disodium EDTA, Butylene Glycol, Carbomer, Xanthan Gum

Frequently Asked Questions

Yes, this serum is suitable for all skin types, including sensitive and oily skin. It's a perfect serum for those wanting anti-aging results without a heavy feel or irritation.

Yes, this serum pairs perfectly with retinoids in your evening routine. Apply serum first, allow to absorb fully before applying retinoid.

Consistency and patience is key. You will start to notice results in a few weeks but we recommend using 2X a day for 6-8 weeks to see real results.

Apply to slightly damp skin as the first step in your AM & PM routine after cleansing and toning.

Absolutely! This serum will prolong results of your injectables. If you do not get injectables, this makes for a perfect non-invasive alternative option.

Skin Concerns

  • Redness
  • Firmness
  • Wrinkles
  • Dryness
  • Post Procedure

Skin Types

  • Normal
  • Dry
  • Combination
  • Oily

How to Layer Your DRMTLGY Products

The Perfect Additions to Any Routine

Customer Reviews

Based on 4110 reviews
92%
(3786)
6%
(231)
1%
(44)
1%
(25)
1%
(24)
M
Maria A.
Age: 40 - 55
Skin type: Sensitive, Combination
Loving this serum

I added this serum to my evening skincare routine since I am not able to use retnoids and I find it is great applied right after shower to hydrated skin and it will be a staple in my skincare routine going forward for years to come. Thank you Drmtlgy and I just ordered the other serum Vitamin C one to incorporate in my morning skincare routine before applying my daily SPF.

S
Susan McManaman
Age: 55+
Skin type: Normal
So easy!

I love this serum. It goes on smooth and makes my face so soft immediately. It only takes a few drops. You will love it!

K
Kylie F.
You need this in your life

My skin has never looked better. I cannot go without this product!!!

A
Anne Korfas
Age: 40 - 55
Skin type: Normal
Needleless Serum

Amazing! My skin is left feeling and looking dewy.

C
CathyLee
Age: 55+
Skin type: Dry
Needless serum

Surprised how much I like this, leaves a slight glow, and tightens my skin, and moisturizes all at the same time.
Will keep using twice a day.

123

Best Selling Bundles