Clinically proven to visibly improve the look of aging skin, Needle-less® Growth Factor Serum features 5 bio-engineered peptides inspired by the skin’s natural renewal processes. This biotech-powered formula helps enhance the appearance of firmness, smooth texture, and a more youthful-looking complexion.
Clinically shown to improve the look of firmness and texture in 8 weeks
Visibly smooths and firms the appearance of skin
Revitalizes the look of skin for a more youthful appearance
Inspired by the skin’s natural renewal signals to improve the look of elasticity
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Clinically proven to visibly improve the look of aging skin, Needle-less® Growth Factor Serum features 5 bio-engineered peptides inspired by the skin’s natural renewal processes. This biotech-powered formula helps enhance the appearance of firmness, smooth texture, and a more youthful-looking complexion.
Clinically shown to improve the look of firmness and texture in 8 weeks
Visibly smooths and firms the appearance of skin
Revitalizes the look of skin for a more youthful appearance
Inspired by the skin’s natural renewal signals to improve the look of elasticity
Before and After 12 Weeks Of Use
When using the Needle-less® Growth Factor Serum as directed. Unedited and not retouched. Results may vary.
4 Reasons You’ll Love Needle-less® Growth Factor Serum
1. Mimics the Skin's Natural Regenerative Signals
A blend of 5 bio-engineered growth factor peptides mimics your skin’s repair messengers, encouraging faster cell renewal without the use of human-derived ingredients.
2. Visibly Lifts & Firms
Clinically tested to deliver real results. 90% of participants noticed skin felt firmer, improved clarity & tone, and an improvement in overall appearance in just 12 weeks.*
3. Outperformed the Leading Growth Factor Serum at ¼ the price
In a 12-week IRB-approved, randomized, double-blinded, controlled clinical trial, our formula delivered 30% greater overall visible improvement, without the $295 price tag.
4. Repairs & Strengthens Skin Barrier
This serum features our CeraPep™ Technology, a proprietary blend of ceramides and peptides that restores the barrier’s essential lipids. So not only does this all-new formula lift and firm, but it’s proven to strengthen skin’s barrier after just one use.
Dr. Steven H. Dayan
MD, FACSDr. Dayan on Needle-less® Growth Factor Serum:
In this 12-week clinical study, participants were split into two groups—each applying a different topical treatment twice daily. Preliminary results showed visible improvements in wrinkles, texture, and firmness across both groups. One group used DRMTLGY's product, while the other used SkinMedica’s TNS Advanced+ Serum priced 4x more. However, the formula developed by DRMTLGY demonstrated notably superior results in skin texture and firmness.
The problem with most anti-aging serums is simple: they promise results but rarely prove they work. Many claim to smooth, firm, and lift—but where’s the evidence?
When we created Needle-less® Growth Factor Serum, we set out to do things differently. Instead of adding just another product to the lineup, we took a smarter approach—grounded in advanced technology and proven by real clinical testing.
In a 12-week, double-blind, IRB-approved clinical trial, Needle-less® Growth Factor Serum was tested head-to-head against SkinMedica’s TNS Advanced+ Serum, the industry’s best-known growth factor serum (sold at nearly 4x the price). The results spoke for themselves:
- Investigator-assessed improvements in skin texture and firmness were significantly higher for Needle-less® at both Week 8 and Week 12
- On the Global Aesthetic Improvement Scale (GAIS) at Week 12, Needle-less® Growth Factor Serum showed 30% greater overall improvement than the competitor
- It outperformed the leading growth factor serum in 73% of performance indicators
Directions
Apply 1-2 pumps to clean skin in the morning or evening. Can be used daily or as directed by a physician.
Ingredients
Ingredient Highlights: Sodium Hyaluronate, Palmitoyl Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Ceramide NP, Folic Acid, Phytosphingosine, Ceramide AP, Ceramide EOP, Chiretta (Swertia Chirata) Extract, Mushroom (Tremella Fuciformis) Sporocarp Extract
All Ingredients: Water/Aqua/Eau, Glycerin, Butylene Glycol, Pentylene Glycol, Maltodextrin, Coco-Caprylate/Caprate, Saccharide Isomerate, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Ceramide NP, Folic Acid, Phytosphingosine, Ceramide AP, Ceramide EOP, Triheptanoin, Chiretta (Swertia Chirata) Extract, Phenoxyethanol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C9-12 Alkane, Polyurethane-100, Ethylhexylglycerin, Sodium Hydroxide, Lecithin, Trisodium Ethylenediamine Disuccinate, Acetyl Glutamine, 1,2-Hexanediol, Mushroom (Tremella Fuciformis) Sporocarp Extract, Hydrolyzed Hyaluronic Acid, Decyl Glucoside, Bacillus/Soybean Ferment Extract, Sodium Lauroyl Lactylate, Caprylyl Glycol, Carbomer, Polysorbate 20, Cholesterol, Xanthan Gum
DRMTLGY is dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.
Skin Concerns
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Wrinkles
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Firmness
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Texture
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Dullness
Wrinkles
Firmness
Texture
Dullness
Skin Types
- Normal
- Oily
- Dry
- Combination
How to Layer Your DRMTLGY Products
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Customer Reviews
I've only just started using the serum and I can say that the texture of the serum is very pleasant on the face without irritation. I'm expecting good results because all your products are perfect for me. 😊
Very hydrating and a great texture.
The Serum goes on so smooth. It makes my face feel like a baby‘s butt while filling in all my wrinkles and fine lines. I have this on subscription and use every night. Ive seen improvements in just a few weeks.
This serum has truly smoothed and firmed up my skin. I get compliments regularly on it. Thank you!! Love it!!
This serum packs a punch. I have extremely sensitive skin, that is reddish pink. I have used this for a few months with zero irritation. The texture of my skin has changed and I am beyond thrilled with my results.
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