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Clinically proven to visibly improve the look of aging skin, Needle-less® Growth Factor Serum features 5 bio-engineered peptides inspired by the skin’s natural renewal processes. This biotech-powered formula helps enhance the appearance of firmness, smooth texture, and a more youthful-looking complexion.
Clinically shown to improve the look of firmness and texture in 8 weeks
Visibly smooths and firms the appearance of skin
Revitalizes the look of skin for a more youthful appearance
Inspired by the skin’s natural renewal signals to improve the look of elasticity
Clinically proven to visibly improve the look of aging skin, Needle-less® Growth Factor Serum features 5 bio-engineer...
Clinically proven to visibly improve the look of aging skin, Needle-less® Growth Factor Serum features 5 bio-engineered peptides inspired by the skin’s natural renewal processes. This biotech-powered formula helps enhance the appearance of firmness, smooth texture, and a more youthful-looking complexion.
Clinically shown to improve the look of firmness and texture in 8 weeks
Visibly smooths and firms the appearance of skin
Revitalizes the look of skin for a more youthful appearance
Inspired by the skin’s natural renewal signals to improve the look of elasticity
Clinically proven to visibly improve the look of aging skin, Needle-less® Growth Factor Serum features 5 bio-engineer...
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Before and After 12 Weeks Of Use
When using the Needle-less® Growth Factor Serum as directed. Unedited and not retouched. Results may vary.
4 Reasons You’ll Love Needle-less® Growth Factor Serum
1. Mimics the Skin's Natural Regenerative Signals
A blend of 5 bio-engineered growth factor peptides mimics your skin’s repair messengers, encouraging faster cell renewal without the use of human-derived ingredients.
2. Visibly Lifts & Firms
Clinically tested to deliver real results. 90% of participants noticed skin felt firmer, improved clarity & tone, and an improvement in overall appearance in just 12 weeks.*
3. Outperformed the Leading Growth Factor Serum at ¼ the price
In a 12-week IRB-approved, randomized, double-blinded, controlled clinical trial, our formula delivered 30% greater overall visible improvement, without the $295 price tag.
4. Repairs & Strengthens Skin Barrier
This serum features our CeraPep™ Technology, a proprietary blend of ceramides and peptides that restores the barrier’s essential lipids. So not only does this all-new formula lift and firm, but it’s proven to strengthen skin’s barrier after just one use.
Dr. Steven H. Dayan
MD, FACS
Dr. Dayan on Needle-less® Growth Factor Serum:
In this 12-week clinical study, participants were split into two groups—each applying a different topical treatment twice daily. Preliminary results showed visible improvements in wrinkles, texture, and firmness across both groups. One group used DRMTLGY's product, while the other used SkinMedica’s TNS Advanced+ Serum priced 4x more. However, the formula developed by DRMTLGY demonstrated notably superior results in skin texture and firmness.
The problem with most anti-aging serums is simple: they promise results but rarely prove they work. Many claim to smooth, firm, and lift—but where’s the evidence?
When we created Needle-less® Growth Factor Serum, we set out to do things differently. Instead of adding just another product to the lineup, we took a smarter approach—grounded in advanced technology and proven by real clinical testing.
In a 12-week, double-blind, IRB-approved clinical trial, Needle-less® Growth Factor Serum was tested head-to-head against SkinMedica’s TNS Advanced+ Serum, the industry’s best-known growth factor serum (sold at nearly 4x the price). The results spoke for themselves:
Investigator-assessed improvements in skin texture and firmness were significantly higher for Needle-less® at both Week 8 and Week 12
On the Global Aesthetic Improvement Scale (GAIS) at Week 12, Needle-less® Growth Factor Serum showed 30% greater overall improvement than the competitor
It outperformed the leading growth factor serum in 73% of performance indicators
In other words, this isn’t just another serum with empty promises. It’s clinically proven skincare technology that reframes how we approach aging—helping skin look visibly lifted and visibly renewed.
Ingredients designed for your skin.
Directions
Apply 1-2 pumps to clean skin in the morning or evening. Can be used daily or as directed by a physician.
DRMTLGY is dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.
This serum packs a punch. I have extremely sensitive skin, that is reddish pink. I have used this for a few months with zero irritation. The texture of my skin has changed and I am beyond thrilled with my results.
A
Adrienne Werner
Just Starting
I just started using the Needle-less Growth Factor Serum. I was surprised how lightweight it was. It doesn't feel heavy or tacky on my face. If it performs like my other DRMTLGY products, Tinted Moisturizer with SPF, Pumpkin Enzyme Maske, Brightening Eye Masks, and the all-timt GOAT, Luminous Eye Corrector with SPF I know I won't be disappointed.
M
Michele Hathway
Age:55+
Skin type:Combination
Great!
I love all DRMTLGY products and this is no exception. Every time I try a new brand, I always come back to this one! They are clean, no fragrance go on beautifully and Iove them all! I'm 60 and my skin looks really good. I combine this with peptide cream in the day. I use growth serum at night.
O
OLIVIA E
Age:40 - 55
Skin type:Dry
Needless Growth Factor Serum
I am on my second bottle of this and can't say enough good things about it. The science behind it is why I ordered. I have tried the TNS Growth Factor from Skin Medica and I will say I believe this serum has given me better results at a fraction of the cost for the TNS. My wrinkles have significantly decreased and my skin overall just appears firmer. Will continue to purchase. It is a little pricey but considering all the benefits I believe its worth the price!
B
Brandy L.
Age:40 - 55
Skin type:Dry
OBSESSED!!
Don't hesitate! Buy it!!! Within a week of using it twice a day people were complimenting my skin and asking what I was doing differently.