The Needle-less® Duo

Firm, Smooth & Lift

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$138.00 $110.40
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DRMTLGY

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Target signs of aging from all angles. This powerhouse duo features two of our most advanced formulas—one proven to visibly firm and lift, the other to plump and smooth. Together, they harness cutting-edge ingredients, including bio-engineered growth factor peptides and skin-identical ceramides, to transform the look of aging skin. Add them both to your routine and discover visibly firmer, more youthful-looking skin in as little as 12 weeks.*
  • Visibly smooths fine lines & wrinkles
  • Visibly lifts & firms skin
  • Helps to improve the look of elasticity
  • Helps reduce redness and even skin tone
Target signs of aging from all angles. This powerhouse duo features two of our most advanced formulas—one proven to v...

As we age, skin can show visible signs of slowed renewal. Fine lines become more noticeable, elasticity feels diminished, and hydration is harder to maintain. That’s where this duo of clinically proven anti-aging formulas comes in.


Needle-less® Growth Factor Serum is formulated with 5 bio-engineered growth factor peptides inspired by the skin’s natural renewal signals to revitalize skin for a more youthful appearance. In head-to-head clinical testing:

90% of participants showed visible improvement*
73% of performance indicators showed DRMTLGY outperformed the $295 leading growth factor serum*

Needle-less® Serum is an award-winning serum that helps bind moisture, visibly smooth fine lines, and support barrier reinforcement through targeted hydration dynamics. In clinical testing after just 6 weeks:

94% saw healthier-looking skin**
91% had firmer-feeling skin**
94% said skin felt smoother**

 

Used together, these serums encourage visible skin renewal, deliver a firmer, more lifted appearance, plump lines with hydration, and help maintain a healthy skin barrier to prevent future moisture loss.

*Based on a 12-week IRB-approved double-blind clinical trial of 20 participants.
**Based on a 6-week independent consumer panel.

Directions

Step 1:
Apply 4 to 5 drops of Needle-less® Serum to a clean, slightly damp face. Avoid getting too close to the eyes. Allow to absorb.
 
Step 2:
Apply 1–2 pumps of Needle-less® Growth Factor Serum and allow to absorb before continuing with the rest of your routine.

 

Both products can be used morning and/or evening.

Ingredients

Ingredient Highlights:
 
Needle-less® Growth Factor Serum:
Sodium Hyaluronate, Palmitoyl Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Ceramide NP, Folic Acid, Phytosphingosine, Ceramide AP, Ceramide EOP, Chiretta (Swertia Chirata) Extract, Mushroom (Tremella Fuciformis) Sporocarp Extract
 
Needle-less® Serum:
Niacinamide (Vitamin B3), Hyaluronic Acid (Sodium Hyaluronate), Methyl Glucoside Phosphate Proline Lysine Copper Complex, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Sodium Chondroitin Sulfate, Glycosaminoglycans, Pea Extract, Glucosamine HCI, Panthenol (Provitamin B5), Bambusa Vulgaris Leaf/Stem Extract
 
All Ingredients:
 
Needle-less® Growth Factor Serum:
Water/Aqua/Eau, Glycerin, Butylene Glycol, Pentylene Glycol, Maltodextrin, Coco-Caprylate/Caprate, Saccharide Isomerate, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Ceramide NP, Folic Acid, Phytosphingosine, Ceramide AP, Ceramide EOP, Triheptanoin, Chiretta (Swertia Chirata) Extract, Phenoxyethanol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C9-12 Alkane, Polyurethane-100, Ethylhexylglycerin, Sodium Hydroxide, Lecithin, Trisodium Ethylenediamine Disuccinate, Acetyl Glutamine, 1,2-Hexanediol, Mushroom (Tremella Fuciformis) Sporocarp Extract, Hydrolyzed Hyaluronic Acid, Decyl Glucoside, Bacillus/Soybean Ferment Extract, Sodium Lauroyl Lactylate, Caprylyl Glycol, Carbomer, Polysorbate 20, Cholesterol, Xanthan Gum
 
Needle-less® Serum:
Water, Glycerin, Sodium Chondroitin Sulfate, Sodium Hyaluronate, Pisum Sativum (Pea) Extract, Bambusa Vulgaris Leaf/Stem Extract, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Glucosamine HCl, Glycosaminoglycans, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Phytosphingosine, Cholesterol, Niacinamide, Sodium Lauroyl Lactylate, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Panthenol, Tocopheryl Acetate, Phenoxyethanol, Polysorbate 20, Ethylhexylglycerin, Disodium EDTA, Butylene Glycol, Carbomer, Xanthan Gum
 
DRMTLGY is dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.

Skin Concerns

  • Wrinkles
  • Firmness
  • Texture
  • Dullness
  • Redness
  • Dryness
  • Post Procedure

Skin Types

  • Normal
  • Dry
  • Oily
  • Combination

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Customer Reviews

Based on 4530 reviews
91%
(4105)
6%
(277)
1%
(60)
1%
(43)
1%
(45)
A
Anonymous
Age: 55+
Skin type: Normal
Skin Concern: Fine lines & wrinkles, Loss of firmness, Dryness or dehydration
Needleless Serum is a must have item!

This is a fabulous product. I ordered an extra for my travel kit.

R
Ruth Daines
Age: 55+
Skin type: Sensitive
Skin Concern: Fine lines & wrinkles, Loss of firmness
Product Usage Duration: 3+ months
Great product for facial lines

I was looking up how to help with lip lines and I kept seeing this product advertised or suggested so I thought I would try it. I was surprised it felt like putting water onto my face and I didn’t know how it could help but my skin loves it. With continued use I noticed my skin looked better and the lines softer. I have rosacea and it doesn’t bother my sensitive skin. I can even put it under my eyes which is very rare for me. My skin absorbs the product well and definitely is improved with the use of this product. I’ve used it a couple years now and would recommend.

K
Kim Steel
Age: 55+
Skin type: Combination
Best serum

I have older skin and find the serums really beneficial for my skin, with no irritations, just beautiful skin

R
Robin
Age: 40 - 55
Skin type: Dry
This serum actually makes a noticeable difference

This serum actually makes a noticeable difference in the smoothness of your skin. The first week or so your skin will feel extra dry and kind of peel-y and then it becomes ridiculously soft and smooth!

C
Carolyn
Age: 40 - 55
Skin type: Sensitive
fantastic product morning and night

Have used this fantastic product morning and night after I washed my face for the last four years. I have Sensitive skin and have never had a problem when using this oil.

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