DRMTLGY's Needle-Less Serum vs. Vitamin C E + F: What You Need to Know

Your favorite "skinfluencers" might make the world of beauty look easy, but if you're new to skincare, it probably feels like anything but. 

Walking down the aisles of your favorite beauty store might leave you convinced you need to buy everything off the shelves, for instance. Or you might just want someone to tell you what works best for you, but you're not sure who to ask.

If you feel this way, this blog post is for you. Our two most popular products, the Needle-Less Serum and Vitamin C E + F, are gentle enough for skincare novices with the most sensitive skin but they're effective enough to be a mainstay in a seasoned expert's regimen.

But if you need more information before you take out your wallet, keep reading. Here, we'll talk about some key facts about each product, how they're different from similar products on the market today, and how to use them in a simple skincare routine. 

So, without further ado, let's get into it! 

A Closer Look at the Needle-Less Serum

The best-selling Needle-Less Serum, or NLS for short, is a lightweight and gentle serum that can be used twice a day to help counteract classic signs of aging, including fine lines, dullness, dryness, and texture. 

In addition to workhorse skincare ingredients like niacinamide and hyaluronic acid, NLS is also formulated with our proprietary Cerapep Technology. Our tried-and-true cocktail of peptides and ceramides slow down the look of aging by adding moisture and firmness back into your skin. 

What does this mean for you? As your skin ages, science has shown that it requires certain ingredients in order to look and perform at its best. Our team has created a formula with precisely the right blend and proportions of ingredients to meet those needs. 

Still, even the most effective products won't do much for you if you hate the way it applies. That's why we've made sure that the Needle-Less Serum is also non-greasy, non-comedogenic, quickly absorbed, and gentle on your skin. What's not to love?

Here's What You Should Know about Vitamin C E + F

Although the Needle-Less Serum is by far our most popular product, the Vitamin C E + F is also hard to beat. Its cutting-edge formula combines some of the best antioxidants on the market today — vitamin C, vitamin E, and ferulic acid — to counteract free radical damage, hyperpigmentation, and those pesky fine lines. 

But what exactly is so great about these three ingredients together? When used together, studies have shown that they can multiply the effects of other antioxidants as much as 8x. This means you'll see results far and away above serums that only use one or two of them. 

You might have seen other high-end vitamin C serums use this specific combination of antioxidants, but DRMTLGY offers it at a mere fraction of the cost of those luxury brands (which means you can stretch out your skincare budget even further!). Plus, we've gone a step further and added a peptide complex to further hydrate and smooth out your skin. 

However, here's one thing you'll want to keep in mind when using C E + F:

The specific kind of vitamin C used (pure l-ascorbic acid, for all you skincare junkies) works best at a low pH, but it's also notoriously unstable. So, you'll want to avoid exposing this product to sunlight, heat, and oxygen, as well as using it with other exfoliators. Otherwise, you'll risk reducing its effectiveness. 

So where's the best place to store this finicky serum? Ideally, you want to put it in a cool place away from sunlight and heat (so definitely not your bathroom), and try not to leave the bottle open while using it. Although it sounds like a hassle, the results this product gives are well worth the effort. 

Why These Two Products are a Match Made in Skincare Heaven

Although the entire DRMTLGY line is designed to improve the overall look of mature skin, these two products do so without resorting to harsh exfoliants — an important detail to consider if you have sensitive skin or just want an effective, uncomplicated routine. 

Like all of our other products, they're also:

  • Not tested on animals
  • Dermatologist-recommended
  • Free of fragrances, gluten, parabens, and sulfates

Most importantly, the Needle-Less Serum and Vitamin C E + F work for virtually everyone. 

The ingredients in each product are chosen specifically for their nourishing and rejuvenating properties: Ceramides and hyaluronic acid restore your skin's moisture levels, while powerful antioxidants work to turn back the clock on your appearance and prevent further free radical damage. 

Adding the NLS and C E + F to your everyday routine can drastically change the look and feel of your skin — plus how you look and feel in your skin too. 

How to Use the Needle-Less Serum and Vitamin C E + F in Your Routine

Both products work their best on a cleansed and toned face. We recommend applying a few drops of Vitamin C E + F in the morning, because the antioxidants in the formula help protect your skin from UV and environmental damage. Of course, you'll want to top it off with your favorite sunscreen to make sure your skin's adequately protected

Use the Needle-Less Serum at night after cleansing and toning, and before moisturizing. You can even use it in combination with your favorite exfoliating products, since NLS plays well with others. 

Here's a skincare hack you'll want to remember: Apply Needle-less Serum to slightly damp skin. Because Needle-less Serum is rich in hyaluronic acid, an ingredient that absorbs 1000 times its weight in water, this trick helps increase the amount of water your skin drinks in.

But if you're just starting out, don't throw both of them into your routine just yet — yes, even though it's tempting. Anytime you add a new product to your regimen, you want to ease into it for about two weeks to make sure you don't have an allergic reaction to any of the ingredients. 

So introduce one product at a time and don't change up any other parts of your skincare routine in the meantime, and soon enough, you'll be working your product lineup like a pro. 

To learn more about how to use these products in combination with the rest of your routine, make sure to check out our guide on layering skincare products. And for more detailed questions, don't be afraid to ask our skincare experts

Skincare can be complicated, but it doesn't have to be. That's why we're here to help. 


Indian Dermatology Online Journal, July-August 2016, Volume 7, Issue 4, pages 311-315

Dermato-endocrinology, July 2012, Volume 4, Issue 3, pages 308-319

Indian Dermatology Online Journal, April 2013, Volume 4, Issue 2, pages 143-146

Cosmeceuticals and Cosmetic Practice, November 2013, Chapter 10

All information is created for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment.