Clinically proven to visibly improve the look of aging skin, Needle-less® Growth Factor Serum features 5 bio-engineered peptides inspired by the skin’s natural renewal processes. This biotech-powered formula helps enhance the appearance of firmness, smooth texture, and a more youthful-looking complexion.
Clinically shown to improve the look of firmness and texture in 8 weeks
Visibly smooths and firms the appearance of skin
Revitalizes the look of skin for a more youthful appearance
Inspired by the skin’s natural renewal signals to improve the look of elasticity
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Clinically proven to visibly improve the look of aging skin, Needle-less® Growth Factor Serum features 5 bio-engineered peptides inspired by the skin’s natural renewal processes. This biotech-powered formula helps enhance the appearance of firmness, smooth texture, and a more youthful-looking complexion.
Clinically shown to improve the look of firmness and texture in 8 weeks
Visibly smooths and firms the appearance of skin
Revitalizes the look of skin for a more youthful appearance
Inspired by the skin’s natural renewal signals to improve the look of elasticity
Before and After 12 Weeks Of Use
When using the Needle-less® Growth Factor Serum as directed. Unedited and not retouched. Results may vary.
4 Reasons You’ll Love Needle-less® Growth Factor Serum
1. Mimics the Skin's Natural Regenerative Signals
A blend of 5 bio-engineered growth factor peptides mimics your skin’s repair messengers, encouraging faster cell renewal without the use of human-derived ingredients.
2. Visibly Lifts & Firms
Clinically tested to deliver real results. 90% of participants noticed skin felt firmer, improved clarity & tone, and an improvement in overall appearance in just 12 weeks.*
3. Outperformed the Leading Growth Factor Serum at ¼ the price
In a 12-week IRB-approved, randomized, double-blinded, controlled clinical trial, our formula delivered 30% greater overall visible improvement, without the $295 price tag.
4. Repairs & Strengthens Skin Barrier
This serum features our CeraPep™ Technology, a proprietary blend of ceramides and peptides that restores the barrier’s essential lipids. So not only does this all-new formula lift and firm, but it’s proven to strengthen skin’s barrier after just one use.
Dr. Steven H. Dayan
MD, FACSDr. Dayan on Needle-less® Growth Factor Serum:
In this 12-week clinical study, participants were split into two groups—each applying a different topical treatment twice daily. Preliminary results showed visible improvements in wrinkles, texture, and firmness across both groups. One group used DRMTLGY's product, while the other used SkinMedica’s TNS Advanced+ Serum priced 4x more. However, the formula developed by DRMTLGY demonstrated notably superior results in skin texture and firmness.
The problem with most anti-aging serums is simple: they promise results but rarely prove they work. Many claim to smooth, firm, and lift—but where’s the evidence?
When we created Needle-less® Growth Factor Serum, we set out to do things differently. Instead of adding just another product to the lineup, we took a smarter approach—grounded in advanced technology and proven by real clinical testing.
In a 12-week, double-blind, IRB-approved clinical trial, Needle-less® Growth Factor Serum was tested head-to-head against SkinMedica’s TNS Advanced+ Serum, the industry’s best-known growth factor serum (sold at nearly 4x the price). The results spoke for themselves:
- Investigator-assessed improvements in skin texture and firmness were significantly higher for Needle-less® at both Week 8 and Week 12
- On the Global Aesthetic Improvement Scale (GAIS) at Week 12, Needle-less® Growth Factor Serum showed 30% greater overall improvement than the competitor
- It outperformed the leading growth factor serum in 73% of performance indicators
Directions
Apply 1-2 pumps to clean skin in the morning or evening. Can be used daily or as directed by a physician.
Ingredients
Ingredient Highlights: Sodium Hyaluronate, Palmitoyl Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Ceramide NP, Folic Acid, Phytosphingosine, Ceramide AP, Ceramide EOP, Chiretta (Swertia Chirata) Extract, Mushroom (Tremella Fuciformis) Sporocarp Extract
All Ingredients: Water/Aqua/Eau, Glycerin, Butylene Glycol, Pentylene Glycol, Maltodextrin, Coco-Caprylate/Caprate, Saccharide Isomerate, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Ceramide NP, Folic Acid, Phytosphingosine, Ceramide AP, Ceramide EOP, Triheptanoin, Chiretta (Swertia Chirata) Extract, Phenoxyethanol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C9-12 Alkane, Polyurethane-100, Ethylhexylglycerin, Sodium Hydroxide, Lecithin, Trisodium Ethylenediamine Disuccinate, Acetyl Glutamine, 1,2-Hexanediol, Mushroom (Tremella Fuciformis) Sporocarp Extract, Hydrolyzed Hyaluronic Acid, Decyl Glucoside, Bacillus/Soybean Ferment Extract, Sodium Lauroyl Lactylate, Caprylyl Glycol, Carbomer, Polysorbate 20, Cholesterol, Xanthan Gum
DRMTLGY is dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.
Skin Concerns
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Wrinkles
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Firmness
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Texture
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Dullness
Wrinkles
Firmness
Texture
Dullness
Skin Types
- Normal
- Oily
- Dry
- Combination
How to Layer Your DRMTLGY Products
Complete Your Regimen
Customer Reviews
Absolutely love this needless growth serum. My face looks greater than before 🙌 thank DRMTLGY for making this amazing serum
Well, this is one of those products that has the payoff with long consistent use. I’ve been using it for a couple of months now and I do think my skin overall looks healthier and bouncier. I used to only at night and then decided to start using it morning at night and I just really like how it feels when it goes on and the immediate plumping effect. But overtime my skin has a more resilient view to it. I’m less prone to fine lines. I’m not sure yet how well it affects laxity. I feel like copper peptides (from a different brand) andDRMTLGY’s neck serum have had the more positive effects in that area.
Silky and has transformed my skin. It's radiant and buttery smooth! I've used it with the peptide night cream as my first order from here about 2 weeks ago. My skin has never looked this good!! I even told so many people about these products in 2 weeks before I even knew about the referring rewards 😂😅
No makeup in this pic. That's how awesome this line is!!!
I've only used it for 2 weeks, but this and the Peptide Night Cream have totally transformed my skin!! I have sensitive, combo, acne prone and hormonal skin. I'm so glad I found this line. I can't wait to try other things!
I started using this product a few weeks ago and can already see a reduction in fine lines.
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