Needle-less® Serum

Firming Plumping Serum

BEST SELLER
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1 fl oz

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Visibly smoother and deeply hydrated skin—no injections needed. This award-winning anti-aging serum was developed with a multi-active system that helps bind moisture, visibly smooth fine lines, and support barrier reinforcement through targeted hydration dynamics.

  • Visibly plumps and smooths fine lines
  • Deeply hydrates and reinforces the skin barrier
  • Targets dullness and redness
Visibly smoother and deeply hydrated skin—no injections needed. This award-winning anti-aging serum was developed wit...

4 Reasons Everyone Loves Needle-less® Serum

001

Cosmo’s “Best Peptide Serum”

This serum works. But don't take our word for it—Cosmopolitan named it the "Best Peptide Serum" in 2023.

002

Dramatic Anti-aging Results You Can See

This active-packed serum is loaded with anti-aging superstars like Hyaluronic Acid, Niacinamide, and our proprietary Cerapep® Technology: a revolutionary blend of restorative peptides & ceramides.

003

Visibly Diminishes Fine Lines

Enriched with potent actives clinically proven to visibly improve the look of fine lines and wrinkles around the mouth, eyes, and forehead.

004

Brighten the Look of Pigmentation

Niacinamide strengthens the skin’s moisture barrier, while improving the look of pigmentation and pore appearance.

Dramatic Anti-aging Results You Can See After 6 Weeks

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94%
saw healthier-looking skin
91%
had firmer-feeling skin
94%
said skin felt smoother
*Based on a six-week independent consumer panel.
Needle-less Serum Before Needle-less Serum After

Before and After 60 Days Of Use

When used as directed. Unedited and not retouched. Results may vary.

As skin matures, it can begin to look less firm and smooth, with more visible lines and uneven texture. Daily exposure to environmental stressors can also weaken the skin’s protective barrier, making it more prone to dryness and visible redness.

Needle-less® Serum was formulated to address these visible signs of aging and support the skin’s barrier to prevent moisture loss. This dual-action formula helps improve the appearance of firmness, visibly smooth texture, and deliver lasting hydration.

Key Facts

  • Absorbs quickly and layers well under other treatments or moisturizer
  • Fragrance-free and suitable for all skin types
  • Can be used day and/or night


Skincare Technology

CERAPEP® TECHNOLOGY
A revolutionary blend of restorative peptides & ceramides

NIACINAMIDE
Helps even skin tone

COPPER PEPTIDE COMPLEX
Enhances skin renewal and firmness

SODIUM HYALURONATE
Penetrates deeply, attracts water and hydrates skin

Directions

  • Apply 4 to 5 drops onto fingers and smooth over a slightly damp face. Avoid getting too close to the eyes.
  • Allow to absorb before applying additional products.
  • Can be used twice a day or as directed by a physician.

Ingredients

Ingredient Highlights

Niacinamide (Vitamin B3), Hyaluronic Acid (Sodium Hyaluronate), Methyl Glucoside Phosphate Proline Lysine Copper Complex, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Sodium Chondroitin Sulfate, Glycosaminoglycans, Pea Extract, Glucosamine HCI, Panthenol (Provitamin B5), Bambusa Vulgaris Leaf/Stem Extract

 

All Ingredients

Water, Glycerin, Sodium Chondroitin Sulfate, Sodium Hyaluronate, Pisum Sativum (Pea) Extract, Bambusa Vulgaris Leaf/Stem Extract, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Glucosamine HCl, Glycosaminoglycans, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Phytosphingosine, Cholesterol, Niacinamide, Sodium Lauroyl Lactylate, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Panthenol, Tocopheryl Acetate, Phenoxyethanol, Polysorbate 20, Ethylhexylglycerin, Disodium EDTA, Butylene Glycol, Carbomer, Xanthan Gum

DRMTLGY is dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.


Skin Concerns

  • Redness
  • Firmness
  • Wrinkles
  • Dryness
  • Post Procedure

Skin Types

  • Normal
  • Dry
  • Combination
  • Oily

Frequently Asked Questions

Yes, this serum is suitable for all skin types, including sensitive and oily skin. It's a perfect serum for those wanting anti-aging results without a heavy feel or irritation.

Yes, this serum pairs perfectly with retinoids in your evening routine. Apply serum first, allow to absorb fully before applying retinoid.

Consistency and patience is key. You will start to notice results in a few weeks but we recommend using 2X a day for 6-8 weeks to see real results.

Apply to slightly damp skin as the first step in your AM & PM routine after cleansing and toning.

Absolutely! This serum will prolong results of your injectables. If you do not get injectables, this makes for a perfect non-invasive alternative option.

How to Layer Needle-less® Serum

Customer Reviews

Based on 4502 reviews
91%
(4083)
6%
(275)
1%
(61)
1%
(42)
1%
(41)
M
Mieka
Age: 30 - 39
Skin type: Combination
My go to

I have been using this product for over 3 years now. I absolutely LOVE it, and have received compliments on my skin ever since starting it.

L
Lauren L.
Everyday essential!

Seriously obsessed!!! Does everything they say they do!

L
Lauren L.
Everyday essential

Makes you plumped!

S
Someone’s mom
Age: 30 - 39
Skin type: Oily, Combination
I fear I am hooked on this

I started using this every other day alternating with retinol in May and have gradually moved to using it every day primarily on my forehead, around my eyes, smile lines, and neck lines with retinol over top and my elevens are now a faint “one” and my forehead lines have significantly improved. I am going to start working in the growth serum into my routine and hope for even better results. This stuff is amazing.

K
Katie S.
Eliminates Redness

I use this serum as part of my morning routine and it has completely eliminated my redness.