Visibly smoother and deeply hydrated skin—no injections needed. This award-winning anti-aging serum was developed with a multi-active system that helps bind moisture, visibly smooth fine lines, and support barrier reinforcement through targeted hydration dynamics.
Visibly plumps and smooths fine lines
Deeply hydrates and reinforces the skin barrier
Targets dullness and redness
Visibly smoother and deeply hydrated skin—no injections needed. This award-winning anti-aging serum was developed wit...
Free U.S. Shipping Over $40 and a 60 day guarantee!
If you don't love it, return it within 60 days for a full-refund - just contact us and we'll take care of you
Visibly smoother and deeply hydrated skin—no injections needed. This award-winning anti-aging serum was developed with a multi-active system that helps bind moisture, visibly smooth fine lines, and support barrier reinforcement through targeted hydration dynamics.
Visibly plumps and smooths fine lines
Deeply hydrates and reinforces the skin barrier
Targets dullness and redness
Visibly smoother and deeply hydrated skin—no injections needed. This award-winning anti-aging serum was developed wit...
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4 Reasons Everyone Loves Needle-less® Serum
001
Cosmo’s “Best Peptide Serum”
This serum works. But don't take our word for it—Cosmopolitan named it the "Best Peptide Serum" in 2023.
002
Dramatic Anti-aging Results You Can See
This active-packed serum is loaded with anti-aging superstars like Hyaluronic Acid, Niacinamide, and our proprietary Cerapep® Technology: a revolutionary blend of restorative peptides & ceramides.
003
Visibly Diminishes Fine Lines
Enriched with potent actives clinically proven to visibly improve the look of fine lines and wrinkles around the mouth, eyes, and forehead.
004
Brighten the Look of Pigmentation
Niacinamide strengthens the skin’s moisture barrier, while improving the look of pigmentation and pore appearance.
Before and After 60 Days Of Use
When used as directed. Unedited and not retouched. Results may vary.
As skin matures, it can begin to look less firm and smooth, with more visible lines and uneven texture. Daily exposure to environmental stressors can also weaken the skin’s protective barrier, making it more prone to dryness and visible redness.
Needle-less® Serum was formulated to address these visible signs of aging and support the skin’s barrier to prevent moisture loss. This dual-action formula helps improve the appearance of firmness, visibly smooth texture, and deliver lasting hydration.
Key Facts
Absorbs quickly and layers well under other treatments or moisturizer
Fragrance-free and suitable for all skin types
Can be used day and/or night
Skincare Technology
CERAPEP® TECHNOLOGY A revolutionary blend of restorative peptides & ceramides
NIACINAMIDE Helps even skin tone
COPPER PEPTIDE COMPLEX Enhances skin renewal and firmness
SODIUM HYALURONATE Penetrates deeply, attracts water and hydrates skin
Ingredients designed for your skin.
Niacinamide (Vitamin B3)
A multifaceted ingredient with numerous skin care benefits.
Hyaluronic Acid
A naturally occurring carbohydrate in the human body that is responsible for keeping skin plump and hydrated.
Copper Peptides
Helps with multiple signs of aging.
Glycosaminoglycans
Fundamental components of skin tissue, essentially a group of complex proteins.
Pea Extract
Provides antioxidant and anti-inflammatory benefits.
Glucosamine HCI
These compounds have been reported to have several beneficial effects on the skin or skin cells.
Sodium Chondroitin Sulfate
Used as a skin-conditioning agent.
Bambusa Vulgaris Leaf/Stem Extract
The richest source of natural Silica.
Panthenol
Also known as Vitamin B5, is effective as a skin lubricant, emollient, and moisturizer.
Ceramides AP, NP, EOP
Naturally occurring long chains of fatty acids (lipids) that improve the look and feel of dry skin.
Palmitoyl Tripeptide-1
Synthetic fatty acid-linked peptide.
Palmitoyl Tripeptide-5
Synthetic peptide that plays a role in the appearance of skin firmness.
Palmitoyl Tripeptide-7
Synthetic peptide comprised of four amino acids and fatty acids.
Phytosphingosine
A moisturizing phospholipid.
Directions
Apply 4 to 5 drops onto fingers and smooth over a slightly damp face. Avoid getting too close to the eyes.
Allow to absorb before applying additional products.
Can be used twice a day or as directed by a physician.
DRMTLGY is dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.
Frequently Asked Questions
Yes, this serum is suitable for all skin types, including sensitive and oily skin. It's a perfect serum for those wanting anti-aging results without a heavy feel or irritation.
Yes, this serum pairs perfectly with retinoids in your evening routine. Apply serum first, allow to absorb fully before applying retinoid.
Consistency and patience is key. You will start to notice results in a few weeks but we recommend using 2X a day for 6-8 weeks to see real results.
Apply to slightly damp skin as the first step in your AM & PM routine after cleansing and toning.
Absolutely! This serum will prolong results of your injectables. If you do not get injectables, this makes for a perfect non-invasive alternative option.
Frequently Asked Questions
Yes, this serum is suitable for all skin types, including sensitive and oily skin. It's a perfect serum for those wanting anti-aging results without a heavy feel or irritation.
Yes, this serum pairs perfectly with retinoids in your evening routine. Apply serum first, allow to absorb fully before applying retinoid.
Consistency and patience is key. You will start to notice results in a few weeks but we recommend using 2X a day for 6-8 weeks to see real results.
Apply to slightly damp skin as the first step in your AM & PM routine after cleansing and toning.
Absolutely! This serum will prolong results of your injectables. If you do not get injectables, this makes for a perfect non-invasive alternative option.
The Needless Duo is so moisturizing & effective in reducing fine lines. I will continue to purchase & they both work well together. I will continue to purchase.
P
Patricia
Age:55+
Skin type:Dry
Must have
Can’t be without it!
K
Kathleen Downs
Age:55+
Skin type:Normal
Nice Product
I am liking this product so far. Just started using it so I'll se how it works.
S
Stephanie Arguin
Age:18 - 29
Skin type:Normal
LOVE IT
I love this product so much. I look forward to applying it at night. It’s very convenient to use and I have been seeing a pretty huge difference since starting using it a few months ago. Highly recommended!!!