How to repair damaged skin barrier?

To repair a damaged skin barrier, focus on replenishing essential lipids, restoring hydration, and using barrier-supporting ingredients. Needle-less® Serum features CeraPep™ Technology, a proprietary blend of skin-identical ceramides and targeted peptides that replenish lost lipids and help strengthen the barrier for healthier, more resilient skin. With daily use, the serum visibly smooths texture, improves firmness, and restores overall balance and comfort.

What causes redness on the face?

Facial redness can be caused by a weakened skin barrier, irritation, overuse of harsh products, environmental stressors, or sensitivity. Needle-less® Serum helps calm visible redness using soothing ingredients like niacinamide, which strengthens the moisture barrier while reducing discoloration and improving the look of uneven tone. Its hydrating and barrier-supporting formula helps the skin appear more balanced and less reactive.

How to soothe irritated skin?

To soothe irritated skin, prioritize gentle, hydrating, and barrier-repairing ingredients. Needle-less® Serum is formulated to visibly calm and comfort the skin with niacinamide, barrier-strengthening ceramides, and deeply hydrating sodium hyaluronate. These ingredients work together to reduce visible redness, replenish moisture, and restore a feeling of balance to irritated or stressed skin.

What are peptides in skincare?

Peptides are short chains of amino acids that act as messengers in skincare, signaling the skin to support renewal, firmness, and elasticity. Needle-less® Serum includes a targeted peptide blend within its CeraPep™ Technology, designed to help visibly smooth fine lines, refine texture, and improve the look of firmness. Combined with ceramides, these peptides help strengthen the skin barrier while promoting a more youthful, revitalized appearance.

How to minimize pores naturally?

To naturally minimize the appearance of pores, you need ingredients that refine texture, balance oil, and support a strong skin barrier. Needle-less® Serum contains niacinamide—a clinically backed ingredient known for reducing visible pore size by strengthening the moisture barrier and evening out the skin’s surface. Its combination of peptides, ceramides, and hydrating actives helps smooth texture for a more refined, radiant complexion.

How to repair the skin barrier?

Repairing the skin barrier starts with replenishing essential lipids, boosting hydration, and calming visible redness. Needle-less® Serum uses our proprietary CeraPep™ Technology—a blend of skin-identical ceramides and targeted peptides—along with niacinamide and sodium hyaluronate to help restore the barrier’s natural lipids, deliver deep hydration, and visibly smooth and firm the skin. With consistent use, it supports a stronger, more resilient, and healthier-looking skin barrier.

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Needle-less® Serum

Firming Plumping Serum

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$69.00

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Needle-less® Serum

Firming Plumping Serum

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1 fl oz

Experience smoother, firmer, and deeply hydrated skin—no injections required. This multitasking serum combines our proprietary CeraPep™ Technology with targeted peptides, ceramides, and sodium hyaluronate to visibly refine texture, calm visible redness, and support a healthy-looking skin barrier. It’s a simplified solution that helps skin look more radiant, balanced, and youthful.

Visibly softens the look of fine lines and wrinkles
Improves the appearance of firmness and elasticity
Energizes dull-looking skin for a refreshed appearance
Helps reduce visible redness and soothe sensitive-looking skin

Experience smoother, firmer, and deeply hydrated skin—no injections required. This multitasking serum combines our pr...

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$69.00

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Visibly softens the look of fine lines and wrinkles
Improves the appearance of firmness and elasticity
Energizes dull-looking skin for a refreshed appearance
Helps reduce visible redness and soothe sensitive-looking skin

Experience smoother, firmer, and deeply hydrated skin—no injections required. This multitasking serum combines our pr...

4 Reasons Everyone Loves Needle-less® Serum

1. Cosmo’s “Best Peptide Serum”

This serum works. But don't take our word for it—Cosmopolitan named it the "Best Peptide Serum" in 2023.

2. Dramatic Anti-aging Results You Can See

This active-packed serum is loaded with anti-aging superstars like Hyaluronic Acid, Niacinamide, and our proprietary Cerapep® Technology: a revolutionary blend of restorative peptides & ceramides.

3. Visibly Diminishes Fine Lines

Enriched with potent actives clinically proven to visibly improve the look of fine lines and wrinkles around the mouth, eyes, and forehead.

4. Brighten the Look of Pigmentation

Niacinamide strengthens the skin’s moisture barrier, while improving the look of pigmentation and pore appearance.

Before and After 60 Days Of Use

When used as directed. Unedited and not retouched. Results may vary.

As skin matures, it can begin to look less firm and smooth, with more visible lines and uneven texture. Daily exposure to environmental stressors and overuse of harsh products can also weaken the skin’s protective barrier, making it appear more prone to dryness and visible redness. Needle-less® Serum was created to help address these visible signs of aging and restore a look of balance, comfort, and vitality.

Our proprietary CeraPep™ Technology combines three skin-identical ceramides with a targeted peptide blend to replenish essential lipids and support the look of a stronger, more resilient skin barrier. This dual-action formula helps improve the appearance of firmness, visibly smooth texture, and deliver lasting hydration. To further calm and refine the complexion, we included niacinamide, a form of vitamin B3 known to help reduce visible redness, minimize the look of pores, and promote an even-looking tone.

Deep hydration is essential for maintaining a youthful-looking complexion. Sodium hyaluronate, a form of hyaluronic acid with a smaller molecular weight, attracts and retains moisture to help visibly plump and smooth the look of fine lines. Meanwhile, pea extract and copper peptides help improve the appearance of elasticity and radiance for a more revitalized look.

Whether you’re looking to extend the benefits of your professional treatments or prefer a non-invasive option, Needle-less® Serum seamlessly fits into any skincare routine.

Ingredients designed for your skin.

Niacinamide (Vitamin B3)

A multifaceted ingredient with numerous skin care benefits.

Hyaluronic Acid

A naturally occurring carbohydrate in the human body that is responsible for keeping skin plump and hydrated.

Copper Peptides

Helps with multiple signs of aging.

Glycosaminoglycans

Fundamental components of skin tissue, essentially a group of complex proteins.

Pea Extract

Provides antioxidant and anti-inflammatory benefits.

Glucosamine HCI

These compounds have been reported to have several beneficial effects on the skin or skin cells.

Sodium Chondroitin Sulfate

Used as a skin-conditioning agent.

Bambusa Vulgaris Leaf/Stem Extract

The richest source of natural Silica.

Panthenol

Also known as Vitamin B5, is effective as a skin lubricant, emollient, and moisturizer.

Ceramides AP, NP, EOP

Naturally occurring long chains of fatty acids (lipids) that improve the look and feel of dry skin.

Palmitoyl Tripeptide-1

Synthetic fatty acid-linked peptide.

Palmitoyl Tripeptide-5

Synthetic peptide that plays a role in the appearance of skin firmness.

Palmitoyl Tripeptide-7

Synthetic peptide comprised of four amino acids and fatty acids.

Phytosphingosine

A moisturizing phospholipid.

Directions

Apply 4 to 5 drops onto fingers and smooth over a slightly damp face. Avoid getting too close to the eyes.
Allow to absorb before applying additional products.
Can be used twice a day or as directed by a physician.

Ingredients

Ingredient Highlights

Niacinamide (Vitamin B3), Hyaluronic Acid (Sodium Hyaluronate), Methyl Glucoside Phosphate Proline Lysine Copper Complex, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Sodium Chondroitin Sulfate, Glycosaminoglycans, Pea Extract, Glucosamine HCI, Panthenol (Provitamin B5), Bambusa Vulgaris Leaf/Stem Extract

All Ingredients

Water, Glycerin, Sodium Chondroitin Sulfate, Sodium Hyaluronate, Pisum Sativum (Pea) Extract, Bambusa Vulgaris Leaf/Stem Extract, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Glucosamine HCl, Glycosaminoglycans, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Phytosphingosine, Cholesterol, Niacinamide, Sodium Lauroyl Lactylate, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Panthenol, Tocopheryl Acetate, Phenoxyethanol, Polysorbate 20, Ethylhexylglycerin, Disodium EDTA, Butylene Glycol, Carbomer, Xanthan Gum

DRMTLGY is dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.

Frequently Asked Questions

Yes, this serum is suitable for all skin types, including sensitive and oily skin. It's a perfect serum for those wanting anti-aging results without a heavy feel or irritation.

Yes, this serum pairs perfectly with retinoids in your evening routine. Apply serum first, allow to absorb fully before applying retinoid.

Consistency and patience is key. You will start to notice results in a few weeks but we recommend using 2X a day for 6-8 weeks to see real results.

Apply to slightly damp skin as the first step in your AM & PM routine after cleansing and toning.

Absolutely! This serum will prolong results of your injectables. If you do not get injectables, this makes for a perfect non-invasive alternative option.

Skin Concerns